Safeway 3375 Jefferson St, Napa, CA94558 This Safeway faces Trancas Street in northern Napa, near Ross and Staples, though the address is 3375 Jefferson…More Street. It is a 24-hour, full-service grocery with a bakery, meat and seafood departments and a pharmacy. The modern store is well-stocked, with ethnic food, fresh produce and organic food sections, and it features self-check-out. It has a Starbucks with Wi-Fi, and the pharmacy offers travel immunizations and flu shots. The store is open 24 hours, except for the pharmacy.